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Whiting reaction : ウィキペディア英語版
Whiting reaction

The Whiting reaction is an organic reaction converting a propargyl diol into a diene using lithium aluminium hydride.〔Nayler, P.; Whiting, M. C. ''J. Chem. Soc.'' 1954, 4006–09.〕
This organic reduction has been applied in the synthesis of ''fecapentaene''.〔''Synthesis of crystalline (.+-.)-fecapentaene'' Hans Rudolf Pfaendler, Franz Karl Maier, and Sonja Klar J. Am. Chem. Soc.; 1986; 108(6) pp. 1338–39. ()〕〔a mutagenic glyceryl ether lipid which can occur in trace amounts in the feces of people living in industrialized countries and are suspected to be a cause for colon cancer〕〔protecting groups are tetrahydropyranyl and TBSMS, the final step is deprotection with tetra-n-butylammonium fluoride
==References==


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